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Screening For Left Ventricular Dysfunction May Have Less Value Than Thought
The value and cost-effectiveness of screening for left ventricular (LV) dysfunction remains unclear, particularly since specific, evidence-based treatments are not available for the majority of patients with preserved systolic dysfunction, reports a study in the June issue of the Journal of Cardiac Failure, published by Elsevier.
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London Health Service Begins Offering Rapid HIV Tests
Barts and the London NHS Trust has become the first National Health Service provider in the United Kingdom to offer rapid, oral HIV tests, BBC News reports. Officials hope that the service will increase the number of people who seek testing because requirements of giving blood and waiting for test results are eliminated with the rapid tests. Barts will offer the rapid, oral tests in non-health care settings such as outreach centers. In addition, sexual health workers hope to be able to offer the test in night clubs in the future. About 200 people in Barts clinics have received rapid tests since March, and officials hope to test 250 people monthly. Merle Symonds, the sexual health adviser at the trust, said the message that HIV is a treatable disease has not "filtered through and stigma does remain around HIV, even if it is waning." Lisa Power of the Terrence Higgins Trust -- an HIV/AIDS organization that also offers rapid, oral tests -- said that a major problem surrounding HIV/AIDS in the United Kingdom is that many people are not aware of their status. She added, "Anything we can do to increase the take-up of testing is welcome, and we think what Barts is doing is fantastic."According to BBC News, the United Kingdom has the largest number of people living with HIV in Western Europe, with men who have sex with men accounting for 41% of new cases. BBC News reports that approximately one-third of HIV-positive people in the country are not aware of their status (BBC News, 5/20).
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QIAGEN To Supply Molecular Screening Solutions To Increase Safety Of Blood Donations In Brazil
QIAGEN (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) announced that it has entered into an agreement to supply molecular sample and assay technologies for a new national, PCR-based blood screening program for HIV and Hepatitis C (HCV) in Brazil. QIAGEN will provide Bio-Manguinhos, the main provider of vaccines and diagnostics to the Brazilian Ministry of Health, with a significant volume of molecular testing solutions - sample and assay technologies, related instrumentation, operational know-how and training. Following the approval by the Brazilian patent authorities, the agreement will run for five years and contains options for subsequent extensions.

MS Society-Funded Study Investigates Experiences Of Partners Of People With MS.

An MS Society-funded study has highlighted the impact that MS has on partners" lives and demonstrates the need for support and services for partners of people with MS. A study recently published in the journal Multiple Sclerosis has concluded that partners of people in the early stages of MS report feeling isolated and helpless. The study involved conducting telephone interviews with 15 people whose partners were recently diagnosed with MS and asking them a series of broad open-ended questions such as "Can you start by telling me all about what you thought and felt when your partner was first diagnosed with MS?" The interviews covered aspects of participants" lives that ranged from feelings when their partner was first diagnosed to the impact of MS on various aspects of their lives and also with how they cope with these challenges.

Scientists And Clinicians Meet To Understand "Rain Man".

UQ"s Queensland Brain Institute (QBI) will host a workshop tomorrow Tuesday July 14 for clinicians and scientists seeking to better understand the syndromes associated with a brain development condition made famous in the movie Rain Man. The workshop will feature some of the world"s leading experts in development of the corpus callosum - the largest fibre tract in the brain, which connects neurons in the left and right cerebral hemispheres. Malformation and absence (agenesis) of the corpus callosum are rare developmental disorders that result in a wide spectrum of symptoms, ranging from severe cerebral palsy, epilepsy and autism to relatively mild learning problems. The Hollywood screenplay Rain Man was inspired by the very real abilities of an American man, Kim Peek, whose brain lacks a corpus callosum. Whole body vibration machines

NovImmune Successfully Completes NI-0801 Phase I Clinical Study.

NovImmune, an immunology-focused biotech company dedicated to the development of therapeutic monoclonal antibodies, announced the successful completion of the first phase I clinical study with its fully human monoclonal antibody NI-0801 targeting the chemokine IP-10 (CXCL10) in healthy volunteers. The randomized, doubleblinded, placebo controlled, single centre, phase I study of escalating single intravenous doses of NI-0801 in healthy volunteers (study NI-0801-01) demonstrated that NI-0801 is well tolerated at doses up to and including 20mg/kg. Chemokines are a group of low molecular weight proteins that induce the chemotaxis of different leukocytes to sites of injury or infection. IP-10 is constitutively expressed at low levels in thymic, splenic and lymph node stroma tissues, but its expression can be induced on a variety of cell types including endothelial cells, keratinocytes, fibroblasts, monocytes and neutrophils. IP-10 not only mediates leukocyte recruitment, but also drives T-cell proliferation upon antigenic stimulation.

Increase In Thyroid Cancer Not Explained By Screening Alone.

Studies have reported an increasing incidence of thyroid cancer since 1980. One possible explanation for this trend is increased detection through more widespread and aggressive use of screening tests. Researchers at the American Cancer Society analyzed thyroid cancer incidence between 1988 and 2005 using the National Cancer Institute"s (NCI"s) Surveillance Epidemiology and End Results (SEER) dataset. They found incidence rates increased for all sizes of tumors, suggesting that screening is not the only explanation for the rise. The highest rate of increase was for primary tumors smaller than 1.0 cm, which rose nearly 10 percent per year among men from 1997 and 2005, and nearly 9 percent/year from 1988 to 2005 among women. Incidence of tumors 4 cm or larger increased more than 3.5 percent per year from 1988 to 2005 among men and 5.7 percent per year from 1988 to 2005 among women.