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Total Sleep Time Not Increased By Regular Daily Exercise, Study Finds
According to a research abstrac presented on June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, days with increased activity were followed by nights with lower total sleep time (TST), while nights with lower TST were followed by increased activities during the next day.
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Quest Diagnostics Introduces First Comprehensive Laboratory Test To Analyze KRAS, NRAS, And BRAF Gene Mutations In Reflex Testing Service
Quest Diagnostics Incorporated (NYSE: DGX), the world"s leading cancer diagnostics company, today launched the EGFR Pathway test (KRAS with reflex to NRAS, BRAF), the first laboratory-developed test from a national commercial reference laboratory for comprehensively identifying, in a single reflex test offering, genetic mutations in the KRAS, NRAS and BRAFL genes. The test is designed to aid the identification of the roughly half of all metastatic colorectal cancer (mCRC) patients who, because of certain mutations of the epidermal growth factor receptor (EGFR) pathway, are believed to be unresponsive to anti-EGFR cancer therapies for mCRC. While some commercial laboratory tests for predicting anti-EGFR response analyze certain mutations of the KRAS and BRAF genes, such as codons 12 and 13 of KRAS, the Quest Diagnostics test detects mutations in codons 12, 13 and 61 of both the KRAS and NRAS genes and mutations in exons 11, 12, and 15 of the BRAF gene, in a sequential reflex manner.
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Power3 Medical Announces Better Than Expected Results For Early Stage Diagnosis Capability Of The NuroPro(R) PD Test For Parkinson's Disease
Power3 Medical Products, Inc. (OTCBB: PWRM), announced that results for the early stage diagnosis from clinical validation trials of the NuroPro® PD test for Parkinson"s disease are better than expected. The NuroPro PD test was developed to help clinicians distinguish patients with Parkinson"s disease from "normal" individuals and patients with other neurological disorders. The NuroPro PD test, developed by Power3, utilizes a panel of blood serum protein biomarkers evaluated by biostatistical analysis to predict the probability that a patient has Parkinson"s disease. The test is intended to solve a critical challenge facing physicians, clinicians, and patients for a quick, early stage and accurate diagnosis of the debilitating disease known as Parkinson"s.
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Agendia To Present Multiple Predictive And Prognostic Studies On Breast And Colorectal Cancers At ASCO Annual Meeting

Agendia, a world leader in molecular cancer diagnostics, today announced that leading researchers from Agendia, the University of California San Francisco and the Netherlands Cancer Institute will present data from multiple studies at the American Society of Clinical Oncology Annual Meeting, May 29 - June 2, 2009, in Orlando, Florida. The study results further underpin the broad predictive and prognostic power of Agendia"s breast cancer recurrence test MammaPrint(R) and highlight promising data on Agendia"s new colon cancer recurrence test, ColoPrint(TM). Visitors can meet the Agendia team in booth #2014 and study results will be discussed at the following sessions: Date: Saturday, May 30, 2009 ORAL PRESENTATION Abstract #512 Time: 5:00PM - 5:15PM Location: Level 2, West Hall D1 The 70-gene profile and chemotherapy benefit in 1,600 breast cancer patients R. A. Bender, M. Knauer, E. J. Rutgers, A. M. Glas, F. A. de Snoo, S. C. Linn, L. J. Van "t Veer Date: Saturday, May 30, 2009 ORAL PRESENTATION Abstract # LBA515 Time: 3:00PM - 6:00PM Location: Level 2, West Hall D1 Breast cancer molecular profiles predict tumor response of neoadjuvant Doxorubicin and Taxol, the I-SPY TRIAL (CALGB 150007/150012, ACRIN 6657) L. J. Esserman, C. Perou, M. Cheang, A. DeMichele, L. Carey, L. J. van "t Veer, J. Gray, E. Petricoin, K. Conway, D. Berry, I-Spy Investigators Date: Saturday, May 30, 2009 POSTER PRESENTATION Abstract #6570 Time: 2:00PM - 6:00PM Location: Level 2, West Hall C Cost effectiveness of targeting chemotherapy with the 70-gene prognostic signature in early stage breast cancer (ESBC) patients K. B. Tong, E. Chen, G. Brink, R. Bender, F. de Snoo, J. Malin Date: Sunday, May 31, 2009 POSTER DISCUSSION Abstract #535 Time: 8:00AM - 12:00PM Location: Level 2, West Hall D1, W240A Outcome prediction by the 70-gene profile in the context of the National Comprehensive Cancer Network (NCCN) guideline F. A. de Snoo, M. Knauer, R. A. Bender, L. Stork-Sloots, E. J. Rutgers, A. M. Glas, S. C. Linn, L. J. Van "t Veer Date: Sunday, May 31, 2009 POSTER PRESENTATION Abstract #4036 Time: 8:00 AM - 12:00 PM Location: Level 2, West Hall C Development and validation of a robust prognostic and predictive signature for colorectal cancer (CRC) patients A. M. Glas, P. Roepman, R. Salazar, G. Capella, V. Moreno, J. Westerga, P. J. Kuppen, I. Simon, L. J. Van "t Veer, R. Tollenaar Date: Sunday, May 31, 2009 POSTER DISCUSSION Abstract #518 Time: 8:00AM - 12:00PM Location: Level 2, West Hall D1, W240A Early determination of metastatic potential in breast cancer: the 70-gene signature in small tumors M. Knauer, S. Mook, V. Retç¨l, M. Kok, J. Wesseling, A. M. Glas, E. J. Rutgers, L. J. van "t Veer, S. C. Linn Date: Monday, June 01, 2009 POSTER PRESENTATION Abstract #11083 Time: 1:00PM - 5:00PM Location: Level 2, West Hall C Combining multi-gene profiling of molecular subtypes with the 70-gene profile for classification of breast cancer L. Stork-Sloots, O. Krijgsman, P. Roepman, F. A. de Snoo, R. A. Bender, A. M. Glas About MammaPrint(R) MammaPrint is the first "in vitro diagnostic multivariate index assay" (IVDMIA) cleared by the U.S. Food and Drug Administration (FDA). FDA clearance requires clinical and analytical validation and reporting systems to ensure patient safety issues are addressed. Highly accurate, MammaPrint identifies patients with early metastasis-patients who are likely to develop metastases within five years following surgery. Several authoritative studies have shown that chemotherapy particularly reduces early metastasis risk. In planning treatment, the MammaPrint test results provide doctors with a clear rationale to assess the benefit of chemotherapy in addition to other clinical information and pathology tests. All MammaPrint tests are conducted in Agendia"s CLIA-accredited service laboratory. Breast cancer recurrence assays currently marketed by other manufacturers have not been subject to the rigorous FDA clearance process. Agendia B.V.


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