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Immune Responses To Flu Vaccine Are Diminished In Lupus Patients
Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs. Because morbidity and mortality related to influenza are increased in immunocompromised patients, it is recommended that patients with SLE get annual flu shots, which are safe and do not increase disease activity. Both antibody and cell-mediated responses are involved in the immune response to influenza; in SLE, antibody responses to the vaccine are diminished, but it is not known if the same effect is seen in cell-mediated responses. A new study was the first to examine cell-mediated responses in SLE patients prior to and following influenza vaccination. The study was published in the August issue of Arthritis & Rheumatism .
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Report Identifies New HIV Cases In Central Florida; County Official Discusses Findings
An annual report by the Health Council of East Central Florida released on Wednesday said that nearly 800 new cases of HIV were reported in Central Florida in 2008 and blacks and Hispanics remain disproportionately affected, the Orlando Sentinel reports. The report was presented to the Ryan White Planning Council, according to the Sentinel. The report said that there are now more than 4,000 people living with HIV in the area, and another 4,400 living with AIDS. In addition, a majority of the new cases of HIV were among blacks and Hispanics, according to the report (Maza, 7/29). In an interview with the Sentinel, Debbie Tucci, the Orange County Health Department"s HIV/AIDS program coordinator, discussed the findings. She said, "HIV/AIDS is not in the forefront the way it used to be. We"ve been talking about this for a long time, and people just don"t think it"s going to happen to them." She added, "The disease doesn"t care what your race or ethnicity is. Now we target minorities more, and what"s happened is that they"re getting tested more. Prevention strategies are absolutely working. There"s always room for improvement, but we"ve come a long way - especially among minorities" (Maza, 7/30).
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Cohesin Jigsaw Begins To Fit
The essential chromosomal protein complex cohesin has crucial roles in sister chromatid cohesion, DNA repair and transcriptional regulation. Despite its conserved function, cohesin"s disparate association patterns in different organisms did not quite add up. New research published in the open access journal Genome Biology works towards completing the cohesin puzzle, reconciling some of these differences.
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Find Additional Funding For 'Flu - British Medical Association

Commenting today on the Finance Minister"s decision that he would not allocate the necessary ÷£55 million funding to combat the swine flu pandemic, Dr Brian Patterson, Chairman of the BMA"s Northern Ireland Council said, "Tackling the pandemic caused by the H1N1 virus is a major public health challenge for Northern Ireland that requires a united response from the Northern Ireland Assembly leadership. "We are deeply concerned at the refusal of Mr Wilson to find additional funding to ensure that Northern Ireland is properly prepared for the predicted rise in "flu cases. There is no option but to fund preparations to tackle the pandemic, and the additional funding must be found, while ensuring that other healthcare services are not impaired in any way". Dr Patterson continued, "The support of the entire Assembly is essential in fighting this pandemic. We have long called for the devolution of health services, and the challenge that swine "flu represents hopefully will prove that our confidence in local accountability is well founded. "As doctors, we will continue to work with the DHSSPS and other healthcare colleagues to provide patient care, but this is becoming increasingly difficult under mounting financial constraints". British Medical Association Northern Ireland


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