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Automated Tissue Engineering On Demand
Skin from a factory - this has long been the dream of pharmacologists, chemists and doctors. Research has an urgent need for large quantities of "skin models", which can be used to determine if products such as creams and soaps, cleaning agents, medicines and adhesive bandages are compatible with skin, or if they instead will lead to irritation or allergic reactions for the consumer. Such test results are seen as more meaningful than those from animal experiments, and can even make such experiments largely superfluous.
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Plastics Chemical Retards Growth, Function Of Adult Reproductive Cells
Bisphenol A, a chemical widely used in plastics and known to cause reproductive problems in the offspring of pregnant mice exposed to it, also has been found to retard the growth of follicles of adult mice and hinder their production of steroid hormones, researchers report.
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American Society of Gene Therapy Names Outstanding New Investigators
The American Society of Gene Therapy recently honored three researchers as Outstanding New Investigators in the field of gene therapy.
Endocrinology

Increase In Thyroid Cancer Not Explained By Screening Alone

Studies have reported an increasing incidence of thyroid cancer since 1980. One possible explanation for this trend is increased detection through more widespread and aggressive use of screening tests. Researchers at the American Cancer Society analyzed thyroid cancer incidence between 1988 and 2005 using the National Cancer Institute"s (NCI"s) Surveillance Epidemiology and End Results (SEER) dataset. They found incidence rates increased for all sizes of tumors, suggesting that screening is not the only explanation for the rise. The highest rate of increase was for primary tumors smaller than 1.0 cm, which rose nearly 10 percent per year among men from 1997 and 2005, and nearly 9 percent/year from 1988 to 2005 among women. Incidence of tumors 4 cm or larger increased more than 3.5 percent per year from 1988 to 2005 among men and 5.7 percent per year from 1988 to 2005 among women. The authors conclude that incidence rates of differentiated thyroid cancers of all sizes increased between 1988 and 2005 in both men and women, and that the increased incidence across all tumor sizes suggests that increased detection through testing is not the sole explanation. Other explanations, including environmental influences and molecular pathways, should be investigated. Article: "Increasing Incidence of Differentiated Thyroid Cancer in the US (1988-2005)." Amy. Y. Chen, Ahmedin Jemal, and Elizabeth M. Ward. CANCER; Published Online: July 13, 2009 (DOI: 10.1002/cncr.24416); Print Issue Date: August 15, 2009 American Cancer Society


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