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Sexual Crimes: Narrow Window For Detection Of Knock-Out Drugs
Drug-facilitated sexual crimes are increasing. The Bonn Institute for Forensic Medicine has recorded that the number of examinations on the use of intoxicants in sexual offences within their catchment area increased 10-fold between 1997 and 2006. In the current edition of Deutsches Arzteblatt International, Burkhard Madea and Frank Musshoff present the modes of action and the detection windows for the most frequent substances (Dtsch Arztebl Int 2009; 106 (20): 341-347).
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Normal Development Of Cells With Abnormal Numbers Of Nuclei
Most of our cells contain a single nucleus that harbors 46 chromosomes (DNA and protein complexes that contain our genes). However, during normal postnatal development, liver cells containing two nuclei, each of which have 46 chromosomes, appear. These cells, which are known as binucleated tetraploid hepatocytes, arise in all mammals as a result of failure of the cellular process cytokinesis (the process by which the bulk of a cell, excluding the nucleus, divides to form two "daughter" cells). New insight into the failure of this process has now been provided by Chantal Desdouets and colleagues, at Institut Cochin, France, who have identified a cellular signaling pathway that leads to cytokinesis failure and the formation of binucleated tetraploid hepatocytes in rodents.
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Insomnia May Be Treated Effectively By Meditation

Meditation may be an effective behavioral intervention in the treatment of insomnia, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies Results indicate that patients saw improvements in subjective sleep quality and sleep diary parameters while practicing meditation. Sleep latency, total sleep time, total wake time, wake after sleep onset, sleep efficiency, sleep quality and depression improved in patients who used meditation. According to principal investigator Ramadevi Gourineni, MD, director of the insomnia program at Northwestern Memorial Hospital in Evanston, Ill., insomnia is believed to be a 24-hour problem of hyperarousal, and elevated measures of arousals are seen throughout the day. "Results of the study show that teaching deep relaxation techniques during the daytime can help improve sleep at night," said Gourineni. The study gathered data from 11 healthy subjects between the ages of 25 and 45 years with chronic primary insomnia. Participants were divided into two intervention groups for two months: Kriya Yoga (a form of meditation that is used to focus internalized attention and has been shown to reduce measures of arousal) and health education. Subjective measures of sleep and depression were collected at baseline and after the two-month period. Both groups received sleep hygiene education; members of the health education group also received information about health-related topics and how to improve health through exercise, nutrition, weight loss and stress management. Abstract Title: Effects of Meditation on Sleep in Individuals with Chronic Insomnia Presentation Date: Tuesday, June 9 Category: Insomnia Abstract ID: 0874 Kelly Wagner American Academy of Sleep Medicine


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