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HESA Performance Indicators Show That 1994 Group Universities Are 'elite But Not Elitist'
1994 Group universities are continuing to widen access to higher education, attracting over 4/5 of their students from state schools for a third consecutive year, as highlighted by statistics published by the Higher Education Statistics Agency (HESA.) As well as increasing their average percentage of entrants from state schools by three times the national average, 1994 Group universities have also achieved drop-out rates well below the sector-wide average for a forth year running, signalling that wider participation and high quality student experience can go hand in hand.
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WFP Appeals For $23M To Help Women, Children In Yemen
The World Food Programme (WFP) issued an urgent appeal on Tuesday for $23 million in "financial support from international donors for food aid to Yemen specifically targeted at women and children," AFP/Google.com reports. The agency said that the "figure represents 42 percent of the 55 million dollars that it needs for the current year to improve the nutrition of more than 1.6 million vulnerable people in Yemen," the news service writes.
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Tamed Virus Wipes Out Cancer Safely
Cancer Research UK scientists have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells, according to a paper published in PLoS Pathogens*.
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Molecular Machinery Related To Stem Cell Fate Revealed By Xie Lab

The Stowers Institute"s Xie Lab has revealed how the BAM protein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition. The work was published by PNAS Early Edition. Maintaining the proper balance between stem cell self-renewal and differentiation is critical for normal homeostasis. An imbalance between the two can lead to tissue degeneration and to the development of tumors. It has long been known that the BAM protein is necessary for germline stem cell differentiation, but the specific molecular mechanism underlying BAM function had remained a mystery until now. Examining the fruit fly ovary, the Xie Lab established that BAM controls stem cell differentiation and competition by interfering with the function of the protein translation initiation factor eIF4A. EIF4A and BAM antagonize each other to regulate the balance between self-renewal and differentiation by promoting proper expression of E-cadherin - a molecule crucial to the stem cell"s ability to attach to its microenvironment (its niche). "Our studies contribute to the understanding of stem cell fate control," said Run Shen, Ph.D., Postdoctoral Research Associate in the Xie Lab and lead author on the paper. "Many protein translation initiation factors have been reported to be unregulated in different human cancer tissues, so our study may help to understand how translational initiation factors participate in stem cell misregulation and the development of tumors." "Our studies have established the role of BAM as a protein translational repressor using biochemical and genetic tests," said Ting Xie, Ph.D., Investigator and senior author on the paper. "Translational control is very important in regulating gene expression. Many genes critical for stem cell development in the fruit fly germline are suggested to be translational regulators, but their exact roles have not been carefully studied. The knowledge generated by this work and the tests we have developed give us great advantage in tackling many additional questions." Ting Xie, Ph.D., Investigator, also is a Professor in the Department of Anatomy & Cell Biology at The University of Kansas School of Medicine. Marie Jennings Stowers Institute for Medical Research


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