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New UCLA Method Predicts Which Brain Tumors Will Respond To Avastin
UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin - before the patient ever starts treatment. By linking high water movement in tumors to positive drug response, the UCLA team predicted with 70 percent accuracy which patients" tumors were the least likely to grow six months after therapy.
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How The Carrot Approach Facilitates Learning
People who are rewarded for making correct decisions learn quickly. While
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ActoGeniX Obtains IND Approval
ActoGeniX, a development stage biopharmaceutical company, announced that the United States÷´ Food and Drug Administration (FDA) has approved the Company÷´s Investigational New Drug (IND) application for AG013, a novel therapeutic product for the treatment of oral mucositis in cancer patients. This IND application approval allows ActoGeniX to initiate a phase 1B clinical trial with AG013, which will now become the second clinical development program in ActoGeniX÷´s portfolio.
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Navigation In Hip Resurfacing

Hip resurfacing can be a good alternative to total hip replacement (THR) in young adults because it conserves bone and it has acceptable short- to medium-term results. However, there have been concerns about fractures of the femoral neck with this procedure, partly due to notching and varus alignment during implantation. Therefore, in this study the author"s used imageless computer navigation as a method to aid in the placement of the femoral component in hip resurfacings. Pre-operative templating was used to determine the planned stem-shaft angle against the native neck-shaft angle. Post-operatively, this template was then assessed using digital anteroposterior unilateral radiographs of the hip. There were no instances of notching of the femoral neck or varus alignment of the implant. The stem-shaft angle differed from that planned by 2.8° and while "a learning curve was observed in the time taken for navigation" this was not true for accurate placement of the implant." The author"s conclude that "computer navigation for placement of the initial guidewire in hip resurfacing has been shown to be more accurate than the use of conventional mechanical jigs" and that it "shows promise in optimising the preparation of the femoral head" and in helping to reduce factors that can cause the femoral neck to fracture and the implant to fail. Read the full text article. The Journal of Bone and Joint Surgery


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