Popular Articles

School Burnout Suffered By One In Five Girls In Upper Secondary School
The transition from basic education to upper secondary school is a challenge for many young people. According to a study of school burnout at different stages of school and higher education, upper secondary school is a particularly challenging stage for many young people. Success-oriented female upper secondary school pupils are at the greatest risk: up to 20 cent of them suffer from school burnout. Burnout is a phenomenon to be taken seriously, as it can lead to depression.
generic viagra online
Medicare Reimbursement Issues Enter Health Reform Debate
New legislation introduced yesterday would attempt to shift Medicare reimbursement policy to reward patient health outcomes, rather than the volume of services provided, MinnPost, a nonprofit online news organization, reports. "We need to be sure to keep score," said Sen. Amy Klobuchar, D-Minn., who introduced the bill, according to MinnPost. "That means measuring outcomes and rewarding providers that deliver quality results."
News of the day
No Adjustment Method Fully Resolves Confounding By Indication, BUSM Researchers Find
Researchers at Boston University School of Medicine (BUSM) and Boston University School of Public Health have found that no adjustment method fully resolves confounding by indication in observational studies, meaning when the validity of a study is threatened by unmeasured confounding, it is not straightforward to determine which method of adjustment, if any, is most effective in obtaining a valid and precise estimate of effect. The study appears online in the Journal of Clinical Epidemiology.
Cardiovascular

The Necessity Of Adrenalectomy At The Time Of Radical Nephrectomy: A Systematic Review

UroToday.com - We undertook a systematic review of the literature in reference to the use of ipsilateral adrenalectomy at the time of radical nephrectomy for the treatment of renal cell carcinoma. Important in the understanding of this is accurately defining.. ..the incidence of solitary, synchronous, ipsilateral adrenal involvement ..the ability of preoperative imaging to detect this ..the morbidity of removal of the adrenal ..the likelihood of identifying preoperative risk factors for adrenal involvement ..survival outcomes with and without adrenalectomy While quoting levels of supporting evidence we attempted to systematically investigate these aspects of the debate. We found that the historical benefit of ipsilateral adrenalectomy does not support it as a standard practice in all patients. The incidence of solitary, synchronous, ipsilateral adrenal involvement, which is potentially curable with ipsilateral adrenalectomy at the time of nephrectomy, is much lower than previously thought at 1 - 5%. Cross-sectional imaging in the current era is accurate in ruling out adrenal involvement but does carry a significant likelihood of false positives. Imaging outcomes are likely to improve with technical advances in imaging. The morbidity and mortality of ipsilateral adrenalectomy are generally minimal, but in those with metastatic disease, especially those developing metachronous contralateral adrenal metastasis, the impact of adrenal insufficiency can be devastating. In direct comparison, disease-specific and overall survival for individuals undergoing radical nephrectomy, with or without adrenalectomy, are similar. Those with multiple high-risk primary tumor features, including high stage/large lesions, upper pole location, multifocality and/or venous invasion may be considered for concomitant adrenalectomy because of the increased prevalence of adrenal metastasis. However, identifying all of these factors preoperatively may be difficult. The survival of those with lymph node positive or metastatic disease is poor regardless of whether adrenalectomy is performed. In these individuals, decisions regarding adrenalectomy should be based upon the desire or indication for cytoreduction. If nephrectomy is warranted, then adrenalectomy could be considered depending on the normality of the adrenal on preoperative imaging, but the benefit should be weighed against the risk of adrenal insufficiency. There is evidence for a survival advantage in patients with isolated adrenal metastasis. This group comprises no more than 2% of patients undergoing surgery for renal cancer. Written by Rebecca O"Malley, MD and Samir S. Taneja, MD as part of Beyond the Abstract on UroToday.com UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):