Nutrition
In a posting aimed at health care professionals, FDA on its Web site on Wednesday said that recipients of Merck"s human papillomavirus vaccine, Gardasil, should be closely observed afterward for 15 minutes while they remain seated or lying down to avoid the possibility of fainting, the Wall Street Journal reports. FDA said that since October 2007, Gardasil"s labeling for both health care providers and patients has included a discussion about fainting. The agency said the strengthened recommendation comes in response to reports of "traumatic injuries" among some recipients who experienced fainting (Corbett Dooren, Wall Street Journal, 6/10). Gardasil protects against the strains of HPV that cause most cases of cervical cancer and genital warts. The Centers for Disease Control and Prevention recommends that girls ages 11 and 12 receive the three-dose vaccine before they are sexually active. Girls and women ages 13 to 26 who have not been vaccinated or completed the vaccine series also should receive the vaccine (CDC fact sheet, June 2008). On Wednesday, FDA also approved changes to Gardasil materials that place warnings about fainting in a more prominent place on drug labels and handouts. The agency said that the new recommendations are intended to "prevent falls and injuries" (Wall Street Journal, 6/10).
Have you ever wished you could be in two places at once? Perhaps you"ve had the desire to create a copy of yourself that could stand in for you at a meeting, freeing you up to work on more pressing matters. Thanks to a research project called LifeLike, that fantasy might be a little closer to reality.
The Hawai"i State Department of Health (DOH) confirmed 83 additional cases of novel H1N1 Influenza A of swine origin this week. Two of the individuals live on the island of Kaua"i, one individual lives on the island of Maui, two individuals live on the island of Hawai"i, and 78 are O"ahu residents. It is important to note that all of the individuals have recovered or are recovering at home with no complications. The next weekly update will be posted at http://www.hawaii.gov/health on Wednesday, June 17 at 11:00 a.m.
Recovering stroke patients and others who find it hard to swallow when they eat and drink are now at a lower risk of developing pneumonia or chest infections, thanks to new technology which will help assess and treat their swallowing difficulties. Many patients suffering from stroke, head injury or major trauma often have swallowing difficulties when food and drink can go down the wrong way - patients can later develop nasty chest infections and pneumonias.
Researchers at Charles Drew University of Medicine and Science in Los Angeles and Western University of Health Sciences in Pomona have discovered a reason why smoking increases the risk of heart disease and strokes.
Operating a computer by thought alone was unimaginable ten years ago, but this incredible feat is now possible. Financed by the ANR (the French national research agency) OpenViBE is the first French multi-partner project on brain-computer interfaces. With support from INRIA (the French national institute for research in computer science and control) and Inserm (the French national institute of health and medical research), OpenViBE has successfully perfected a free software programme with highly promising applications.
In the first large-scale study of its kind, researchers at the University of Michigan"s C.S. Mott Children"s Hospital and the University of Utah will lead a multi-center study to investigate whether hypothermia-lowering body temperature can prevent or reduce brain damage in children deprived of oxygen after a cardiac arrest.
Keeping your baby fat turns out to be a good thing, as long as it is "brown fat"- the kind that burns calories, according to a study that found adults have much more of this type of fat than previously thought. The results, which suggest a new way to treat obesity, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
As the World Health Organization raised the pandemic alert for Influenza A (H1N1) to its highest level, humanitarian specialists are calling on governments and health authorities globally to strengthen poor communities" access to primary health care and protect the most at risk.
In today"s image-obsessed society where millions of photos are uploaded daily through digital networks such as Facebook and Flickr, how much of an impact can a common skin condition like acne have on the life of teens? Based on first impressions, teens with acne are perceived to have different personality and social traits than if they had clear skin, according to results of a new online perception survey sponsored by the American Acne & Rosacea Society (AARS), and co-authored by Dr. Eva Ritvo, psychiatrist and co-author of The Beauty Prescription.(1) The survey asked thousands of teens and adults to offer their impressions of a group of teens based solely on photos of their faces - with clear skin or digitally enhanced to simulate acne. The results, which are being released to mark the first-ever National Acne Awareness Month, also expose the significant lengths that teens with acne would go to if it meant they could get rid of their acne forever.(1a)
When combined with a cocktail of chemotherapy drugs, two monoclonal antibodies, instead of one, appear to offer superior results in patients with diffuse large B-cell lymphoma, according to Mayo Clinic researchers working with the North Central Cancer Treatment Group (NCCTG).
A new era in the National Health Service that builds on targets achieved and prioritises quality of care was set out by new Health Secretary Andy Burnham today.
The health of millions of people worldwide is at risk as a result of the financial crisis, says Dr Andrew Robertson, in an editorial published online in Emerging Health Threats Journal. The world economy is currently in the midst of the most significant recession since the 1930s. The crisis has proved devastating for national economies, and the effects on health care will be felt worldwide as health spending falls, unemployment rises, and international aid is cut.
The National Institute on Drug Abuse of the National Institutes of Health has awarded a three-year, $3-million grant to Albert Einstein College of Medicine of Yeshiva University to establish a research center to study the neurological complications that afflict people infected with HIV, the virus that causes AIDS.
The benefits of alcohol are all about moderation. Low to moderate drinking - especially of red wine - appears to reduce causes of mortality, while too much drinking causes multiple organ damage.
The U.S. Food and Drug Administration is alerting patients to the Class I recall of certain Medtronic Kappa and Sigma pacemakers. These devices may fail due to a separation of wires that connect the electronic circuit to other pacemaker components, such as the battery.
World Blood Donor Day is being celebrated across the world at the weekend (14th June) but there will be nowhere like the walking blood bank on board the world"s largest charity hospital ship.
Insomnia is associated with increased frontal cerebral metabolism during Rapid Eye Movement (REM) sleep. Cerebral hypothermia, or cooling of the brain, has been found to reduce cerebral metabolism in other medical conditions, but its effects in insomnia are unknown.
The World Health Organization declared a swine flu pandemic Thursday, raising its pandemic warning from phase 5 to 6, making swine flu the first global flu epidemic in 41 years. Now that H1N1 "Swine Flu" has been elevated to pandemic status, with reports of outbreaks in Asia, the Middle East and Europe, San Francisco, USA-based Cannabis Science Inc. (OTCBB: CBIS) CEO Steven Kubby urges public health officials around the world to "take medical cannabis seriously."
Pfizer announced today that data from two new mid-stage clinical studies of the company"s oral JAK-3 inhibitor, CP-690,550, showed statistically significant response versus placebo for patients with rheumatoid arthritis (RA). Data from these two Phase 2 trials and one ongoing open-label safety study are being presented this week at the 10th Annual Congress of the European League Against Rheumatism (EULAR). These results confirm findings from two previously reported Phase 2 studies in RA and have been used to support dose selection for Phase 3.
A retrospective analysis conducted by clinicians at Maricopa Integrated Health System (MIHS) found that a protocol of care using a standardized algorithm with advanced products reduced the prevalence of pressure ulcers by 90 percent, according to data presented this week at the 41st Annual Conference of the Wound, Ostomy and Continence Nurses (WOCN) Society.(1)
Alzheimer"s disease patients show a relentless decline in memory over the course of the disease, which is accompanied by both brain atrophy and by characteristic deposits in the brain tissue called amyloid plaques and neurofibrillary tangles. Researchers from the Chinese Academy of Sciences studied a large database, collected in the US, of patients with Alzheimer"s or memory complaints who had MRI scans and had spinal taps to collect cerebrospinal fluid, which is in the brain and spinal chord. By examining the CFS they could measure the amounts of the substances that make p plaques and tangles, and related this to brain atrophy. They found that the amount of plaque and tangle-producing chemicals in the cerebrospinal fluid correlated with brain tissue loss in selective regions of the brain which are typically affected in Alzheimer"s disease. The brains in these regions had thinned out suggesting that brain cells had died. These regions are important for memory and are typically active when the brain is at rest. Using these techniques may ultimately help identify early markers of disease in Alzheimer"s, potentially indicating who is likely to develop Alzheimer"s before memory loss is critical.
In middle-aged and older men with low testosterone levels, long-term testosterone replacement therapy greatly improves their fatty liver disease and their risk factors for cardiovascular disease and diabetes, a new study found. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
In these difficult times, when the global health community is facing the dangers of an important new influenza pandemic, a new partnership is forming. The lancet, one of the world÷´s leading medical journals has announced its partnership with the Rockefeller Foundation and the China Medical Board. Together they will develop a major series to evaluate the state of public health in Southeast Asia.
UroToday.com - The mortality rate for prostate cancer is declining due to improvements in earlier detection and in local therapy strategies, however, the ability to predict the metastatic behavior of a patient"s cancer, as well as to detect and eradicate disease recurrence remains some of the greatest clinical challenges in oncology.
Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resistant to antibiotics.
Globally, millions of people die each year as a result of accidents or serious injury. Unfortunately, many of those deaths could have been prevented had first aid been administered at the scene immediately, before the emergency services arrived. First aid, or emergency first aid is the care that is given to an injured or sick person prior to treatment by medically trained personnel. According to Medilexicon"s medical dictionary, first aid is "Immediate assistance administered in the case of injury or sudden illness by a bystander or other layperson, before the arrival of trained medical personnel."
Thousands of people with Alzheimer"s will continue to be denied access to the only drug treatments for the disease following the publication of revised guidance by the NICE.
The British Psychological Society has today welcomed the announcement by the Health Professions Council (HPC) to set high entry level qualifications for psychologists to be admitted to the forthcoming statutory register of Practitioner Psychologists.
The American College of Nurse-Midwives (ACNM), the nation"s oldest women"s health organization, is pleased to announce that the American College of Obstetricians and Gynecologists (ACOG) has reaffirmed its support for equitable reimbursement for certified nurse-midwives (CNMs) and certified midwives (CMs) within the Medicare program, a priority legislative initiative for ACNM members.
What is sure to be a staggering price tag for health reform has Senate Democrats talking about changing the chamber"s normal accounting procedures, The Hill reports.
Sen. Kent Conrad, who has proposed a cooperative insurance marketplace for Americans and small businesses to pool and purchase health insurance, told The Washington Post"s Ezra Klein yesterday that his co-op proposal worked from the premise that a public plan to purchase health insurance doesn"t have the votes to pass the Senate.
New legislation introduced yesterday would attempt to shift Medicare reimbursement policy to reward patient health outcomes, rather than the volume of services provided, MinnPost, a nonprofit online news organization, reports. "We need to be sure to keep score," said Sen. Amy Klobuchar, D-Minn., who introduced the bill, according to MinnPost. "That means measuring outcomes and rewarding providers that deliver quality results."
New genes discovered by Australian and New Zealand researchers may hold the key to new treatments for people with multiple sclerosis (MS).
Two newspapers recently published an editorial and an opinion piece in reaction to the announcement that murdered Kansas abortion provider George Tiller"s Wichita clinic would be permanently closed. The clinic was one of a handful in the U.S. offering abortion procedures in the second and third trimesters. Summaries appear below.~ Kansas City Star: The closing of Tiller"s clinic is "a tragedy for American democracy," and the "irrational violence" of his death has "trumped public policy," a Star editorial states. "The basis of civilization is that we agree to submit to the rule of law in order for society to flourish," the editorial says, adding that Tiller"s murder is "antithetical to that principle. It is dismaying to see a killer achieve his objective." The editorial notes that Tiller provided abortion services in "tragic cases" involving women "at risk of infertility or death; fetuses with severe abnormalities; and victims of rape and incest." It continues that the "reduction or loss of that service will create hardships and may put women"s lives at risk." Hospitals and doctors who refer such cases to abortion providers "must reassess the circumstances under which they would perform late-term abortions," according to the editorial. In addition, the "medical profession must take a role in training and supporting doctors willing to provide abortions," and the government and local police "must do all they can to protect a legal medical practice," the editorial says. It concludes, "Democracy demands that we not allow murder to make de facto public policy" (Kansas City Star, 6/11).~ Eric Zorn, Chicago Tribune: The announcement that Tiller"s clinic will remain permanently closed "was simply more proof that violence and intimidation can get results where civil discourse and political process fail," Tribune columnist Zorn writes. "The question isn"t whether prominent foes of abortion rights are being honest with us when they decry Tiller"s violent death and express regret over the means used to achieve an end they"ve sought," Zorn writes, adding, "Some are, I"m sure." He continues that abortion-rights opponents "recognize that ... a movement calling itself "pro-life"can"t also be pro-murder" and "are politically savvy enough to know that the gains won by terrorist acts are grudging and difficult to sustain." He continues that to "make terrorism less effective, and thereby discourage it," abortion-rights advocates, the medical profession, politicians and law enforcement officials "need to reopen that clinic in Wichita and assure its safe operation ... to defy terrorism, if for no other reason." He concludes that "as long as abortion remains legal, this same coalition needs to strive to expand the number of facilities where it"s available" (Zorn, Chicago Tribune, 6/11).
Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. Attempts to create a vaccine that induces antibodies that prevent HIV infection or disease, however, have so far been unsuccessful. But several recent studies suggest promising new research directions for the development of an antibody-based HIV vaccine, according to John R. Mascola, M.D., deputy director of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, and colleagues.
Roughly a billion years from now, the ever-increasing radiation from the sun will have heated Earth into inhabitability; the carbon dioxide in the atmosphere that serves as food for plant life will disappear, pulled out by the weathering of rocks; the oceans will evaporate; and all living things will disappear.
Individuals diagnosed with rheumatoid arthritis (RA) in lower gross domestic product (GDP) countries (GDP below $11,000) are more likely to continue working despite higher disease activity and functional disability scores compared to their counterparts in higher GDP countries (GDP >$24,000) according to a new multinational study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.
Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, affecting both the development and the outcome of cancers and other diseases.
New figures from the NHS Information Centre reveal a sobering tally of over 300 heart attacks, 300 strokes, 65 foot or toe amputations and 38 leg amputations among people with diabetes each week.
People over the age of 60 are more likely than younger people to take risks with "use by" dates, according to new research findings published by the Food Standards Agency.
When a patient"s first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255). Furthermore, RA patients with their first symptoms in spring showed poorer radiographic outcome compared to summer-onset patients (OR=2.83 [1.10;7.37], p=0.0322), according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.
Researchers at the Keck School of Medicine of the University of Southern California (USC) have identified a key mechanism that causes chromosomes within blood cells to break - an occurrence that marks the first step in the development of human lymphoma.
The Multiple Sclerosis Society of Canada has made public the creation of five research and training centers with the participation of over one hundred established scientists and two hundred and fifty trainees. Funded entirely by the MS Society of Canada, which has already raised 32 million dollars from a goal of 60 million, the objectives of these new centers is to considerably increase the speed on MS research investigations so that an end to MS may be found as quickly as possible. These centres will serve as key establishments in achieving these goals.
BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced it is filing an application with the U.S. Food and Drug Administration (FDA) for 510(k) clearance to market its Allay™ Menstrual Pain Relief Patch product. The filing follows a very successful double blinded, placebo controlled clinical trial in which 71% of women in the active group reported either complete elimination or a reduction in their typical menstrual pain symptoms, with 49% showing at least a 50% reduction in pain associated with dysmenorrhea.
Jazz Pharmaceuticals" (Nasdaq: JAZZ) sodium oxybate (JZP-6) demonstrated statistically significant and clinically meaningful improvement in pain and the core symptoms associated with fibromyalgia, according to Phase III data presented last week at the 2009 Associated Professional Sleep Societies meeting in Seattle, WA. These data have not been evaluated by the FDA or other regulatory authorities for use of sodium oxybate in the treatment of fibromyalgia.
QLT Inc. (NASDAQ: QLTI; TSX: QLT) announced that twelve-month primary analysis results from the Novartis sponsored Phase II MONT BLANC study were presented on June 14, 2009 during the 17th Congress of the European Society of Ophthalmology in Amsterdam, the Netherlands. MONT BLANC is the European study of the Novartis sponsored SUMMIT clinical trial program which investigates the efficacy and safety of combining Visudyne(R) (Novartis Pharma AG) and Lucentis(R) (Novartis Pharma AG, Genentech Inc.). SUMMIT also includes the DENALI study in the US and Canada and the EVEREST study in Asia. MONT BLANC is a 24-month randomized, double-masked, multicenter trial in patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. The purpose of the study is to evaluate whether Visudyne combined with Lucentis is not inferior to Lucentis monotherapy with respect to the mean change from baseline in visual acuity (VA) and to evaluate the proportion of patients with a treatment-free interval of at least three months duration after Month 2. At the Month 12 examination, mean VA in the Visudyne combination therapy group improved 2.5 letters from baseline compared with a 4.4 letter improvement in the Lucentis monotherapy group. In the combination therapy group, 96% of patients had a three-month treatment-free interval, compared with 92% in the Lucentis monotherapy group.
Novartis has successfully completed the production of the first batch of influenza A(H1N1) vaccine, weeks ahead of expectations. Cell-based manufacturing technology[1] allows vaccine production to be initiated once a pandemic virus strain is identified without the need to adapt the virus strain to grow in eggs, as with traditional vaccine technologies. This advance has cut weeks off the time required to begin vaccine production. This first batch of ten liters of wild type influenza A(H1N1) vaccine monobulk will be used for pre-clinical evaluation and testing and is also being considered for use in clinical trials. It demonstrates the value of the cell-based production approach, that is also being used by Novartis with reassortant influenza A(H1N1) seed.
Sanofi Aventis (Euronext: SAN and NYSE: SNY) and Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) announced that advanced ovarian cancer patients with recurrent symptomatic malignant ascites (SMA) receiving aflibercept (VEGF Trap) in a randomized, placebo-controlled Phase 2 study experienced a statistically significant improvement in the primary study endpoint, mean time to first repeat paracentesis (removal of fluid from the abdominal cavity), versus placebo control. Symptomatic malignant ascites is an abnormal build-up of fluid in the abdominal cavity in patients with advanced cancer.
Abbott"s (NYSE: ABT) TRILIPIX® (fenofibric acid) delayed-release capsules in combination with rosuvastatin calcium achieved individual and combined lipid targets in patients with mixed dyslipidemia and type 2 diabetes. In these patients, the combination of TRILIPIX and rosuvastatin helped up to three times more patients simultaneously reach all three key lipid targets HDL, triglycerides and LDL than the pre-determined monotherapy. Results from this post-hoc analysis were presented at the American Diabetes Association"s 2009 Scientific Sessions.
Cheltenham Borough Council has today lost its case to sue former employee Christine Laird for ÷£1million for not disclosing her past experience of depression. Leading mental health charity Mind says the landmark ruling serves as an important reminder to employers about the importance of providing adequate support to people with mental health problems in the workplace.
Medical Protection Society (MPS) GP members, who are expected to work outside of their normal duties during a pandemic flu, should feel confident that they can turn to the MPS for assistance, in the event they are subject to a clinical negligence claim or other medicolegal matter such as a complaint.
Rich Umbdenstock
In his weekly Internet and radio address Saturday, President Obama announced a plan to cut $313 billion in Medicare and Medicaid spending over the next decade as a way to raise money for overhauling the health care system and covering millions of the uninsured, the Los Angeles Times reports. The largest savings include "increased efficiencies in the system," cuts to subsidies paid to hospitals for treating the uninsured, cuts to prices the government pays for prescription drugs for seniors. The paper adds: "the proposal -- which includes potential cuts to hospitals, pharmaceutical companies and other providers -- also underscores the political delicacy of the administration"s search for money for a massive healthcare overhaul that could cost more than $1.2 trillion over the next decade" (Levey, 6/15).
The North Carolina legislature has proposed to eliminate the HIV Medicaid Case Management program, which "provides crucial support to people living with HIV, helping them access medical care, medications and the support services needed to live healthier lives," Jacquelyn Clymore of the Alliance of AIDS Services-Carolina and Beth Stringfield, member of the North Carolina AIDS Action Network, write in a Durham News opinion piece, adding, "We need to call legislators and let them know how important this program is to those living with HIV and ask them to return the program and its funding to the budget." They continue, "It is likely that additional budget cuts to HIV programs will be proposed, and we must speak out in support of state HIV prevention funding" (Clymore/Stringfield, Durham News, 6/13).
UK and US researchers found that more intelligent people are often healthier, and suggest that this could be due to what they describe as a genetic
A low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease, according to researchers at Whitehead Institute for Biomedical Research.
Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.
As Congress drafts health care reform legislation, HIV clinicians urge lawmakers to include a public plan option to ensure affordable access to comprehensive care for HIV patients - nearly 30 percent of whom have no insurance. The HIV Medicine Association (HIVMA) believes that a public plan option can help offer everyone the chance to benefit from early and reliable access to lifesaving HIV care and treatment.
Rexahn Pharmaceuticals, Inc. (NYSE Amex: RNN), announced the results of a wide-ranging animal study offering more evidence that Serdaxin™ may be an effective therapeutic for the treatment of anxiety disorders in humans. Serdaxin is Rexahn"s leading anxiety and depression drug candidate, and is currently in Phase II clinical trials.
The Government has, for the first time, declared its support for what could be England"s first Autism Bill. The National Autistic Society (NAS) celebrated the move as a vital development for people with autism as Care Services Minister Phil Hope committed to enshrining in law a raft of new measures, via the Autism Bill, which could drive a dramatic improvement in local authority and NHS services for people with the condition.
Boston University Biomedical Engineer Joyce Wong will work to create engineered blood vessels aimed at correcting pediatric heart defects under a major grant from The Hartwell Foundation. Wong is one of just 12 researchers nationwide to win the foundation"s prestigious Individual Biomedical Research Award.
Most of our cells contain a single nucleus that harbors 46 chromosomes (DNA and protein complexes that contain our genes). However, during normal postnatal development, liver cells containing two nuclei, each of which have 46 chromosomes, appear. These cells, which are known as binucleated tetraploid hepatocytes, arise in all mammals as a result of failure of the cellular process cytokinesis (the process by which the bulk of a cell, excluding the nucleus, divides to form two "daughter" cells). New insight into the failure of this process has now been provided by Chantal Desdouets and colleagues, at Institut Cochin, France, who have identified a cellular signaling pathway that leads to cytokinesis failure and the formation of binucleated tetraploid hepatocytes in rodents.
Although maintaining the integrity of blood vessel walls is essential for life, well-controlled temporary leakage of blood contents through the walls of blood vessels into the tissues is a hallmark of inflammation. Although the molecule S1P is known to act on the cells that line blood vessels (endothelial cells) to regulate the permeability of blood vessel walls, the in vivo of SIP in this process remains unknown, and whether it has a role in inflammation has not been determined. In a new study, Shaun Coughlin and colleagues, at UCSF, San Francisco, have shed light on these issues, revealing that mice that lack S1P selectively in plasma (the liquid component of blood) have increased leakage from the blood vessels in response to a variety of stimuli, including inflammatory ones. As the leakage was reversed by treatment with either S1P-containing red blood cells or an agonist for the protein to which SIP binds, the authors conclude that S1P in the blood regulates blood-vessel integrity and prevents potentially lethal decreases in blood volume after exposure to leak-inducing stimuli.
Using a highly sensitive new test, scientists in Europe are reporting "convincing evidence" that marijuana smoke damages the genetic material DNA in ways that could increase the risk of cancer. Their study can be found in the June 15 issue of ACS" Chemical Research in Toxicology, a monthly journal.
Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find.
The University of California, San Francisco, has partnered with Abbott, a global health care company, to launch a first-of-its kind, non-profit viral diagnostics center near the UCSF Mission Bay campus to help identify unknown viruses from around the world.
The American Medical Association warmly welcomed U.S. President Barack Obama to its 158th annual meeting in Chicago. Like the president, the AMA is committed to health reform this year that provides all Americans with affordable, high-quality health coverage.
British scientists have developed a unique air purifier, now patented in 36 jurisdictions around the world, which according to independent research can kill the viruses H1N1 Swine Flu and H5N1 Bird Flu within minutes in any room or other enclosed space. It is also effective against the MRSA "superbug" and other airborne bacteria and viruses: Tri-Air Developments
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM) reported that researchers will present data at the SNM 2009 Annual Meeting showing that its brain cancer agent Cotara(R) specifically localizes to brain tumors at high concentrations with minimal radiation exposure to other organs. Cotara is a targeted monoclonal antibody linked to a radioisotope being developed as a potential new treatment for glioblastoma multiforme (GBM), a deadly form of brain cancer. The results reported from an ongoing dosimetry study at U.S. brain cancer centers show that in patients dosed in the first two cohorts of the study, the concentration of Cotara in brain tumors was on average more than 300-fold higher than in other normal organs. In addition, these patients have all either met or exceeded the expected median survival time of six months for recurrent GBM patients. Cotara is currently being tested in this Phase I dose response and dosimetry trial and in a Phase II clinical trial in recurrent GBM patients.
URAC, the leading health care accreditation and education organization, and CARF International, a premier, global, independent accreditor of health and human services, announced a new tool for case management professionals. The uSPEQ(R)/URAC Participant Experience Survey for Case Management (uSPEQ-CM) will help evaluate and improve the quality of health care programs and services offered to consumers.
Researchers at the University of Virginia Health System have found a new way to study how genes function in living organisms, and their approach could substantially cut the time and costs that drug makers spend in searching for potential targets for new cancer therapies.
It is well known that chronic pain and clinical depression go together, but a study in The Journal of Pain, published by the American Pain Society, shows that the connection between pain and depression is strongest in middle-age women and African Americans.
A German study published in The Journal of Pain showed that an external suction technique mainly used outside the U.S., called cupping, is effective for providing temporary relief of pain from carpal tunnel syndrome (CPS).
A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans.
A nurse has been sentenced to 9 months" imprisonment at Liverpool Crown Court (15th June, 2009) for obtaining an NHS bursary and then employment in a private nursing home using forged documents, after overstaying his leave to remain in the UK. The conviction follows an investigation by NHS Counter Fraud.
A fee for patients at Cleveland Clinic is upsetting some patients who are complaining to the Ohio hospital, their insurance companies and even members of Congress. They say they can"t afford the expense in the current economy, according to The Plain Dealer.
A group of 50 families will ask lawmakers this week to keep in mind 9 million uninsured children and many more who are underinsured when they undertake health reform this summer, the Cincinnati Enquirer reports. "Covering all children, and making sure they have access to the care they need regardless of their family"s financial situation or where they live, is an achievable first step toward covering all Americans," the CEO of the Children"s Hospital Association told the Enquirer.
Albany, Ga., health officials are recommending that all residents between the ages of 13 and 64 be tested for HIV as a part of their routine medical care, the Albany Herald reports. Officials are concerned about HIV in Southwest Georgia, as there are large percentages of low-income and black residents in the area -- populations that have been hard hit by the epidemic, according to the Herald. In addition, Chanel Scott-Dixon, HIV/AIDS program manager for Southwest District Health, said, "We have been seeing an increase in young adults testing positive." In observance of National HIV Testing Day on June 27, public health officials will be offering free HIV testing to residents (Parks, Albany Herald, 6/14).
Despite the current global economic crisis, U.N. Secretary-General Ban Ki-moon on Monday called for a continued international commitment to investing in health, Xinhua/People"s Daily reports. "We can cut back on health expenditures and incur massive losses in lives and fundamental capacity for growth. Or we can invest in health and spare both people and economies the high cost of inaction," Ban said during an address at the U.N. Forum on Advancing Global Health in the Face of Crises, a day-long forum at U.N. headquarters in New York. "The cost of cutting back is just unthinkable" (Xinhua/People"s Daily, 6/16).
The U.S. Food and Drug Administration is taking steps to improve contact lens safety by reminding consumers of the importance of following proper cleaning and storing procedures. Consumers who do not follow instructions for contact lens care and use increase their risk of serious eye infections that can lead to blindness.
Children born without thymus glands have given Duke University Medical Center researchers a rare opportunity to watch as a new immune system develops its population of infection-fighting T-cells.
MiCardia® (MiCardia Corporation, Irvine, California) announced the completion of the first U.S. implant of its Dynaplasty® mitral valve repair technology. The surgery was performed last week at Beaumont Hospital, Royal Oak, Michigan. Francis L. Shannon, M.D., who is a partner in SEMCVS and Director of CV Surgical Research and Quality Outcomes at Beaumont, commented, "The MiCardia® device implanted easily and conformed well to the patient"s mitral annulus. The complete D-shaped ring was used to reinforce a complex repair of a flail leaflet segment using minimally invasive techniques. We are excited to be participating in the DYANA Study and believe Dynaplasty® technology will address a major weakness of current devices, namely their inability to deal with changes in valve shape and function after the initial repair procedure."
As panic surrounding the spread of swine flu heightens following the World Health Organization"s declaration of a global pandemic, many may be fooling themselves into believing that their state or national border can provide protection from the virus, based on new research from NYU Stern on people"s tendency to treat arbitrary political boundaries as safeguards.
With one in five, or 60 million, Americans suffering from some kind of allergy, spring and summer can be a difficult time of year as pollen, moisture and humidity increase. According to the Asthma and Allergy Foundation of America, allergies are considered the fifth leading chronic disease and are a major cause of work absenteeism, resulting in nearly four million missed or lost workdays each year.
ARYx Therapeutics Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced today that the database for the EmbraceAC study has been locked and the study remains on schedule, with the efficacy and safety results to be available during the week of July 6, 2009. The study was designed to compare its oral anticoagulation therapy, tecarfarin (previously ATI-5923), against the leading anticoagulant agent, warfarin. The purpose of the trial is to evaluate whether tecarfarin is superior to warfarin in its ability to maintain patients within a target therapeutic range of the level of anticoagulation as measured by INR (International Normalized Ratio). Based upon recent interactions with the U. S. Food and Drug Administration (FDA), ARYx believes this trial could be positioned as one of the required registration studies for tecarfarin.
QuantRx® Biomedical Corporation (OTCBB:QTXB), a broad-based diagnostic company focused on the development and commercialization of innovative diagnostic products, announced that its affiliate, FluoroPharma Inc., a company developing breakthrough PET molecular imaging agents, will present Phase I data relating to the safety, dosimetry, and pharmacokinetics in human subjects of BFPET, its novel 18-F labeled (PET) tracer for myocardial perfusion imaging, at the Society of Nuclear Medicine 2009 Annual Meeting in Toronto.
Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy, according to a study in the June 17 issue of JAMA.
A new diagnostic technique which may greatly simplify the detection of Alzheimer"s disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal"s Jewish General Hospital (JGH). Their results were published June 8 in the Journal of Alzheimer"s Disease. There is currently no accepted blood test for Alzheimer"s, and the diagnosis is usually based on expensive and labour-intensive neurological, neuropsychological and neuroimaging evaluations.
OptumHealth Inc. announced that it is providing a free help line to people in Missouri and Oklahoma who are trying to cope with the emotional consequences of the recent tornadoes that hit the region. Staffed by experienced master"s-level behavioral health specialists, the free help line offers assistance to callers seeking help in dealing with stress, anxiety and the grieving process. Callers may also receive referrals to a database of community res to help them with specific concerns, such as financial and legal issues.
A new study by The George Institute for International Health has found Tai Chi to have positive health benefits for musculoskeletal pain. The results of the first comprehensive analysis of Tai Chi suggest that it produces positive effects for improving pain and disability among arthritis sufferers.
A new study by UK scientists showed that cooking carrots whole preserves their anti-cancer properties better than cooking them sliced or
The emergency use of an investigational drug has yielded promising results in reducing the potentially fatal side effects of the widely used cancer chemotherapy 5-fluorouracil (5-FU), according to clinical data that will be reported June 1 at the annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando.1
More than 13,000 people who have lost the ability to make their own decisions die in Queensland, Victoria and New South Wales each year after doctors have withheld life-sustaining medical treatment such as CPR.
"GW Metabolic Research Laboratory" established in conjunction with Professor Cawthorne and the Clore Laboratory, University of Buckingham
Epeius Biotechnologies announced that its lead product, Rexin-G, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for use as a second-line treatment for advanced or metastatic pancreatic cancer. The FDA Fast Track program, like Priority Review and Accelerated Approval, was implemented to facilitate the development and expedite the review of potentially important new drugs. The Fast Track Product designation, in particular, is granted following a critical evaluation of the "seriousness" or life-threatening nature of the unmet medical need, namely pancreatic cancer, and the potential of Rexin-G and its progressive clinical development to address this unmet need.
Data published in the June issue of the Journal of Alzheimer"s Disease demonstrated that minimally-invasive biospectroscopy was able to identify changes in oxidative stress (OS) levels in blood plasma, which may prove to be a useful biomarker in the early detection of Alzheimer"s disease. There is currently no accepted laboratory test for diagnosing Alzheimer"s disease.
The histamine-3 receptor is important in terms of alcohol-related behaviour, and a drug affecting that receptor may have qualities that alter alcohol-related behaviour. This appears in the study headed by Pertti Panula entitled "Tuberomamillary nucleus neurons, histamine and H3 receptor in hypothalamic regulation of alcohol addiction" which is part of the Substance Use and Addictions research programme of the Academy of Finland.
Hydration expert, Water Wellpoint is playing a key role in helping public sector employers look after the health and wellbeing of their staff. The company has recently been working with East London NHS Foundation Trust to run a series of wellbeing days, giving employees the ability to check key aspects of their health in a total voluntary format.
Brain injuries are the number one killer and disabler of people under the age of 45 in Canada. These injuries are
Food, fitness or familyò€¦which one is most to blame for childhood obesity? New research from Mintel shows today"s parents aren"t sure, and they"re feeling overwhelmed and worried as they try to prevent obesity in their own children.
According to the latest ratings of two watchdog groups, medical schools are "improving their conflict-of-interest policies to police their ties with drug and medical-device makers. But more than half the schools still have inadequate policies or no policies at all," the Wall Street Journal"s Health Blog reports. The American Medical Student Association and the Pew Prescription Project said the number of schools earning top marks had more than doubled, in part because of pressure from lawmakers like Sen. Charles Grassley, R-Iowa. But, "there are a lot of schools that are yet to look seriously at these issues," the director of the Pew project said.
St. Jude Medical, Inc. (NYSE:STJ) announced U.S. Food and Drug Administration (FDA) approval of its Cool Point™ Irrigation Pump. Used in conjunction with SJM open-irrigated ablation catheters, an irrigation pump supplies a continuous flow of saline through the catheter"s inner lumen to cool the ablation electrode for more effective energy delivery. Designed to enhance physicians" ability to perform successful atrial ablations, the new Cool Point irrigation pump was developed specifically for use with the company"s IBI-1500T9-CP cardiac ablation generator and family of Therapy™ Cool Path™ irrigated catheters.
U.N. Secretary-General Ban Ki-Moon during a General Assembly meeting Tuesday urged governments not to cut aid for the international fight against HIV/AIDS, the AP/Washington Post reports. Even as Ban "called for "bold action" not only to increase funding but also to break down social barriers to achieve the goal set by world leaders in 2006 of universal access to comprehensive HIV prevention services, treatment, care and support by 2010," he and other speakers at the meeting "reviewing progress and challenges in the battle against AIDS indicated that it will be exceedingly difficult - if not impossible - to reach the goal" (Lederer, AP/Washington Post, 6/16).
WHO To Investigate Reported Bubonic Plague Cases In Libya
Endocrine Society Unveils First-Ever Scientific Statement: Inaugural Statement Identifies Endocrine-Disrupting Chemicals as a Significant Concern to Public Health
Today, The Endocrine Society announced Newsweek Reporters Barbara Kantrowitz and Patrice Wingert recipients of the Society"s second annual Award for Excellence in Science and Medical Journalism. The co-authors of the winning article, "Uh, O!" (O for Oprah) were honored last night at the Society"s 91st Annual Meeting in Washington, DC.
Health and religion have always been intertwined, most obviously through prayer on behalf of the sick. Does intercessory prayer for sick people actually help heal them? For thousands of years some people have believed so. But new Brandeis University research in the Journal of Religion this month shows that over the last four decades, medical studies of intercessory prayer - the prayer of strangers at a distance - actually say more about the scientists conducting the studies than about the power of prayer to heal.
BioMimetic Therapeutics, Inc. (NASDAQ: BMTI) announced it has submitted both the pre-clinical pharmacology/toxicology and quality/manufacturing modules of its Premarket Approval (PMA) application for marketing of Augment Bone Graft in the U.S. These are two of the three parts, or modules, required for a complete PMA application to the FDA. The Company intends to file the third and final module, containing the clinical data, in the fourth quarter of 2009.
A new study reveals that 900 hypertensive patients using IDEAL LIFE remote health management devices to monitor their blood pressure effectively reduced their systolic blood pressure (SYS) by an average of 10 mmHg (millimeters of mercury). For many patients, this decrease brought them below 140 mmHg, the level traditionally defined as the threshold for "high" blood pressure.
Satellite observation of cloud temperatures may be able to accurately predict severe thunderstorms up to 45 minutes earlier than relying on traditional radar alone, say researchers at the University of Wisconsin-Madison Space Science and Engineering Center.
Arrayit Corporation (OTCBB: ARYC), a leading manufacturer of products and services for disease prevention, treatment and cure, announced that its microarray-based diagnostic test, patented under the trade name Variation Identification Platform (VIP), is ready for manufacture and distribution. A breakthrough screening test using VIP will allow clinicians and researchers to test and detect the H1N1 swine flu virus in population wide studies.
An important breakthrough in fungal toxin biology has been made possible through the use of Biolog"s Phenotype MicroArray technology. This major advance is described in two recent publications from a group at CSIRO in Queensland, Australia. The work by Donald Gardiner and his collaborators has recently been published in online editions of the journals Fungal Genetics and Biology and Microbiology.
Shape is turning out to be a particularly important feature of some commercially important nanoparticles - but in subtle ways. New studies* by scientists at the National Institute for Standards and Technology (NIST) show that changing the shape of cobalt nanoparticles from spherical to cubic can fundamentally change their behavior.